Dicarboxylic acids and derivatives
Apexbio Technology LLC GlyH-101 328541-79-3 10mg
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Selleck Chemical LLC (R)-(-)-Gossypol (AT-101) acetic acid S2812-50mg
(R)-(-)-Gossypol (AT-101) acetic acid the R-(-) enantiomer of Gossypol acetic acid binds with Bcl-2 Bcl-xL and Mcl-1 with Ki of 0 32 M 0 48 M and 0 18 M in cell-free assays does not inhibit BIR3 domain and BID AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy Phase 2
Medchemexpress LLC AVN-101 hydrochlorid 10mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 10 MG
AVN-101 hydrochloride is the hydrochloride salt of AVN-101, a brain-penetrant, orally active antagonist of serotonin 5-HT7 receptors used in preclinical CNS research. It is supplied as a high-purity solid for in vitro and in vivo studies.
- Potent 5-HT7 receptor antagonist with additional activity at 5-HT6, 5-HT2A, 5-HT2C, H1, and α2 adrenergic receptors.
- Brain-penetrant and orally active, suitable for CNS pharmacology studies.
- High purity solid (LCMS purity 99.59%) for reliable experimental results.
- Chemical identity: 1H-pyrido[4,3-b]indole hydrochloride; formula C21H25ClN2; Mw 340.89.
- Recommended storage: sealed at -20°C; solvent storage guidance available from supplier.
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | MFCD00274131 | 98.1% | C19H38ClNO4 | 10MG
Lauroyl-L-carnitine chloride is an orally active absorption enhancer used in research to improve the oral bioavailability of peptide compounds. Supplied as a white to off-white solid with high purity, it is applied in formulation and permeability studies to assess and enhance intestinal uptake of peptide drugs.
- Orally active absorption enhancer for peptide compounds.
- Reported to improve oral bioavailability of peptides.
- White to off-white solid suitable for formulation research.
- High purity (~98.1%) as supplied.
- Supports studies of intestinal permeability and delivery.
- Store sealed at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Lei-101 | 2250025-91-1 | 99.4% | 508.99 g·mol⁻¹ | C23H26ClFN4O4S | 10MG
LEI-101 is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist used in research to investigate CB2-mediated signaling and pharmacology. It exhibits approximately 100-fold selectivity for CB2 over CB1, with a pEC50 of about 8 for human CB2, low hERG affinity, and is supplied as a high-purity white to off-white solid suitable for in vitro and in vivo studies.
- High purity (99.4%).
- Potent CB2 agonist (pEC50 ≈ 8 for hCB2).
- Approximately 100-fold selectivity for CB2 over CB1.
- Low hERG binding (pKi < 4).
- Soluble in DMSO (≈116.67 mg/mL).
- Stable when stored sealed and kept away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
- Provided in milligram-scale quantities for research use.
Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 1 ML
CUDC-101 is a small-molecule inhibitor that targets histone deacetylases (HDAC) and receptor tyrosine kinases EGFR and HER2. It is intended for research use in studies of signaling pathways, anti-proliferative activity, and preclinical cancer models. The compound is supplied as a high-purity reagent suitable for in vitro experiments.
- Multi-target HDAC, EGFR, and HER2 inhibition
- High purity suitable for research applications
- Available as a ready-to-use 10 mM solution in DMSO (1 mL)
- Confirmed molecular formula and molecular weight for analytical workflows
- Intended for in vitro and preclinical research use